American Polish Lowland Sheepdog Association

 CANINE DIVERSITY GENETIC TEST


                      Brought to you by the Health Committee
      of the American Polish Lowland Sheepdog Association (APLSA)
                the Canine Diversity Genetic Test is now available.
In cooperation with the Veterinary  Genetics (VCL) of the University of California , Davis, and in collaboration with Dr.  Niels C. Pedersen an staff, the APLSA has enrolled in Phase I--Research Stage for Genetic Diversity Testing of the PON.

Dr. Pedersen and  staff have developed  a panel of short tandem repeat (DLA) class I and II regions.  This test panel will be useful to the Polish Lowland Sheepdog breeders (ultimately the owners) who wish to track and increase genetic diversity of the breed as a long term goal.  It is a widely accepted principle of genetics that the more genetically diverse a breed is, the healthier the breed will be.  For this reason, rare breeds such as the Alaskan Klee Kai, Kookerhondje, Mi-Ki,  Biewer Yorkshire Terrier, Black Coated Retriever,  as well as some of the more popular breeds like the Havanese, have begun utilizing this test to find out exactly how diverse the  gene pool is for their breed.  This panel will measure the genetic diversity that exists in the PON, will determine internal relatedness (IR) of individuals of this breed and will compare internal relatedness of single dogs to the population as a whole.  The ultimate goal is to select mates that will produce more genetically diverse offspring.


DEVELOPMENT PHASE FOR BUILDING BASELINE DATA
Genetic testing of the Polish Lowland Sheepdog is now in the development phase. During this phase we need to test 100 or more unrelated* Polish Lowland Sheepdogs from disparate geographic regions to acquire the baseline genetic data necessary to provide breeders with an accurate preliminary assessment of genetic diversity in the breed.  We encourage breeders in particular to submit samples  from active dogs to further build the database.  The goal is to test enough dogs so  that no new alleles or DLA haplotypes are recognized. 

*The term "unrelated" is used to mean "as unrelated as possible."  The intent is to get a wide, representative sampling of the population, from as many lines and geographic areas as possible. The Health Committee is hoping breeders  from many different countries will participate in this program and the APLSA is working to make that happen.

Cost of Test
The price for one sample test is $50.00 while in the research phase.  Once the research phase is complete the test will be offered at the regular rate of $80.00.  Results will be reported when sufficient date has been compiled.  





How to Order the Test Kits

The APLSA Officers and Board of Directors  as well as the APLSA Health Committee members highly encourage all PON owners to participate in this worthwhile project.  You can order test kits (a simple swab test) for your PON by :

1)  Go to the website address:  https://www.vgl.ucdavis.edu/myvgl
2)  Click on the "Create Account" link to create a MyVGL account as a
      new customer.
3)  By creating an account, new users will need to complete the
      activation step via email.
4)  After creating an account,  Select "Order Tests" in the top menu bar.
5)  Select "Dog Tests" when it asks you to Select Species  in the second
     menu bar.
6)  Select "Dog Diagnostic"  tests in the list of links.
7)  Click on "Canine Genetic Diversity"  test under the title "Dog
      Diagnostic Tests"
8)  Fill in the online form, press save button at the bottom, and checkout
      or  order more tests.
9)  Detailed instructions for collecting and mailing DNA samples are
     included on the submission form printout.

Payment can be made online via credit card (Visa, Master Card, American Express, and Discover) ; or by check in US funds; or fill out the credit card authorization form included with printed submission form.

Questions about this test can be directed to the APLSA Health Committee or email   coloradopls77@yahoo.com

If you are willing and hopefully you will be, copies of your results can be sent to   aplsaorg@gmail.com


 Please   *******************    Read
The following is a note from the PON Post Editor (official APLSA newsletter):

I cannot encourage each and every PON owner enough to take part in this study.  IF I could get down on bended knee in every home where this is read, I would beg each and every owner to participate for the sake of the health of the breed...Although the study is not designed to search for PRA, diabetes or Cancer, UC Davis has discovered in that some of the breed studies patterns have emerged that were related to specific health issues. being mentioned.   So please, please, please consider taking part. At this point there are no "health tests" per se that have been designed for the PON.  Not only will the UC Davis study help with a starting point for understanding where specific health issues come from, but each and every participant will receive the results of his/her PON's DNA and results will not be shared with anyone else.  APLSA is the "Contact person" for the study and will be the only recipient of the  final report...no specific dogs